Costimulatory molecules CD80 and CD86 play an important role in the activation of T cell mediated by protein carrier, then induced the production of anti-GM1 antibody, and then induced EAN. .

 
  • 協(xié)同刺激分子CD80和CD86的表達通過(guò)載體蛋白活化T細胞,進(jìn)而導致抗GM1-IgG抗體產(chǎn)生,在EAN的發(fā)病中起重要作用。
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