Background and objective: HMGB1(high mobility group box-1),also known previously as HMG1,is a nonhistone nuclear protein identified over 30 years ago and the name simply derives from the fact that it runs fast in SDS-polyacrylamide gels.
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- 研究背景和目的:高遷移率族蛋白B1(high mobility group box-1,HMGB1)曾稱(chēng)為HMG1,是30多年前發(fā)現的非組蛋白核蛋白,因其在凝膠電泳中泳動(dòng)速度快而得名[1]。