Antisense oligonucleotides have been broadly applied in specific inhibition of gene expression in many organs, including liver. 反義寡核苷酸技術(shù)已被廣泛用于在許多組織中抑制特定基因的表達。
Cantide and Flutide are 20-mer and 13-mer antisense phosphorothioate oligonucleotides, which showed significant antitumor activities and antivirus activites in vitro and in vivo. 癌泰得和流感泰得為本室篩選出的兩種具有較好抗腫瘤及抗病毒活性的硫代反義寡核苷酸化合物。
