Among theses targeting moieties, disulfide-stabilized Fv or Fab fragment has disulfide bond to conjoin the heavy chain and the light chain to increase the stablility, but it is difficult to express in host or has a poor yield.
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- 在單鏈抗體、二硫鍵抗體、Fab抗體這幾種導向載體中,二硫鍵抗體、Fab抗體因重鏈和輕鏈之間有二硫鍵相連,穩定性較高,但表達困難或較難獲得較高產(chǎn)量;
