Among the three step (Z-disc split, degradation of damaged protein, protein synthesization )of DOMS, degradation of damaged protein through Ubiquitin-Proteasome Pathway (UPP) is the step that limit the progress rate of DOMS.
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- 在DOMS經(jīng)歷的Z帶撕裂、損傷蛋白質(zhì)降解和蛋白質(zhì)合成三個(gè)主要階段中,損傷蛋白質(zhì)的泛素-蛋白酶體特異性蛋白質(zhì)降解途徑(UPP)降解是主要的限速過(guò)程,而對損傷蛋白質(zhì)UPP降解貢獻最大的是糖皮質(zhì)激素(GC)通路的激活。