After cloning the FUT2 gene by Kelly et al,molecular analyses of FUT2 indicated the non-function alleles (se) which were generated by single base mutation (G428A A385T C57IT C628T,G849A and C658T) caused Se enzyme deficient.

 
  • 1995年Kelly等克隆了FUT2基因后,對FUT2基因的分子分析指出,該基因蛋白編碼區內單個(gè)堿基的突變(G428A,A385T,C571T,C628T,G849A,C658T)產(chǎn)生的無(wú)功能等位基因(se)導致Se酶活性喪失。
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