Adenovirus vectors have the characteristics of high transfection efficiency and low cytotoxicity, and they have become most widely used vectors for gene therapy. 摘要腺病毒載體具有高效轉染和低細胞毒性的特點(diǎn)，已成為基因治療研究中應用最廣泛的載體之一。
However, the clinical application of the third-generation adenovirus vectors is hampered by the existance of helper contamination and difficulties in their large-scale production. 然而，由于輔助病毒污染的存在及病毒產(chǎn)量有待提高，第三代腺病毒載體的臨床應用仍面臨一定困難。
