Aberrant GBM HS expression has been obsered in seeral glomerular diseases, such as diabetic nephropathy and membranous glomerulopathy, and a decrease in HS generally is associated with proteinuria.

 
  • 一些腎小球疾病中曾見(jiàn)到異常腎小球基底膜硫酸乙酰肝素表達,如糖尿病性腎病變和膜性腎小球病,HS減少通常與蛋白尿有關(guān)。
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