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- Angiogenesis inhibitor TNP-470 has strong inhibitory effect on tumor growth of human gastric cancer in nude mice. 2. 結論:TNP-470對胃癌生長(cháng)有抑制作用;
- Purpose To synthesize a new antitumor drug 2-methoxyestradiol which is an angiogenesis inhibitor. 目的合成抗腫瘤新藥新生血管形成抑制劑2甲氧基雌二醇。
- Objective: To study the effect of the angiogenesis inhibitor SU6668 combined with 5-Fu on liver metastasis in human colon cancer. 目的:探討血管生成抑制劑SU6668聯(lián)合5-Fu對人結腸癌肝轉移的抑制作用。
- Conclusions The model for tumor neovascularization has been proved to be reliable for the study of the angiogenesis inhibitor. 結論小鼠腫瘤新生血管模型是一種穩定可靠的新生血管模型。
- The distilling technology and bioactivity of angiogenesis inhibitor components from Dasyatis akajei cartilage were studied primarily. 以赤魟軟骨為原料,對赤魟軟骨中新生血管抑制組分的提取方法及其生物學(xué)活性進(jìn)行了初步研究。
- Conclusion The model for tumor neovascularization has been proved to be reliable for the study of the angiogenesis inhibitor. 結論 小鼠腫瘤新生血管模型是一種穩定可靠的新生血管模型。
- Tumor angiogenesis inhibitor is a class of new drugs that can destroy or inhibit tumor neovascularization,and can effectively block the growth and metastasis of cancer. 腫瘤血管生成抑制劑是一類(lèi)能破壞或抑制血管生成,有效地阻止腫瘤生長(cháng)和轉移的藥物。
- Liu BY, Lin YZ, Yin HR, et al.Experimental study of the effect of angiogenesis inhibitor TNP-470 on the growth and metastasis of gastric[J].Chin J Oncol, 1998, 20(1): 34-6. [6]劉炳亞;林言箴;尹浩然;等.;血管生成抑制劑TNP-470對胃癌生長(cháng)及轉移抑制作用的實(shí)驗研究[J]
- Methods VEGF and bFGF as angiogenic factors, thalidomide asan angiogenesis inhibitor, various properties of vascular endothelialcells (RF/6A and SVEC) were detected in vitro with MTT assay,wound migration assay, invasion assay and tube formation assay. 方法以VEGF,bFGF為血管新生因子,以Thalidomide血管新生抑制因子對體外培養的血管內皮細胞系(RF/6A,SVEC)應用MTT試驗,遷移試驗,浸潤試驗和管狀形成試驗檢測內皮細胞的各種特性;
- Endogenous angiogenesis inhibitors act as tumor suppressor proteins. 內源性血管生成抑制劑可作為一種抑癌蛋白。
- brain-specific angiogenesis inhibitor 腦特異性血管生成抑制因子
- Two angiogenesis inhibitors have been developed that have a broad spectrum of anticancer activity, yet virtually no side effects. 目前,已有兩種具有廣譜抗腫瘤活性且無(wú)明顯副作用的血管生成抑制劑面世。
- Results: Angiogenesis inhibitors have brighter prospects on treatment of lung cancers. 結果:血管生成抑制劑治療肺癌方法可行,前景誘人。
- Several types of angiogenesis inhibitors reveal a biphasic, U-shaped curve of efficacy. 一些類(lèi)型的血管生成抑制劑表現出一種雙向性,成U行曲線(xiàn)的效能。
- Recently, many endogenous angiogenesis inhibitors have been discovered, some of them are currently in various stages of clinical trials. 近年來(lái),研究發(fā)現了多種內源性血管生成抑制因子,其中一些已進(jìn)入了臨床試驗階段。
- This review focused on the structure, function, and mechanism of endogenous angiogenesis inhibitors, and their potential in treating tumor. 本文對內源性血管生成抑制因子的結構、功能、作用機制及其在腫瘤治療中的應用進(jìn)行綜述。
- Studies on the structure and catalytic mechanism of huMetAP 2 provide the basis for design and synthesis of new angiogenesis inhibitors. 根據甲硫氨酰氨肽酶2的結構以及催化和抑制機制,可以設計和合成新型的血管生成抑制劑;
- Human tests of efficacy are under way and will be a much better judge of whether angiogenesis inhibitors can live up to their very great promise. 至于針對藥物效用的人體試驗則正進(jìn)行中,其結果將對這些血管新生抑制劑有更適宜的評價(jià),看看它們是否能不負眾望。
- Men ain't apt to get kicked out of good society for being rich. 人是不會(huì )因有錢(qián)而從上流社會(huì )被趕出去的。
- As the features of angiogenesis inhibitors are of low toxicity and have less acquired resistance,it comes to a new strategy to suppress tumor growth by restraining angiogenesis. 由于抗血管生成藥物具有毒性低、不易產(chǎn)生獲得性耐藥的特點(diǎn)。因此,通過(guò)抑制血管生成來(lái)抑制腫瘤生長(cháng)成為目前腫瘤治療的策略之一。