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- Construction and Expression of Anti human Gastric Cancer mAb 3H11 Fab. 抗胃癌單抗3H11可變區氨基端序列對抗體活性的影響
- Meanwhile, anti human BPI polycolonal antibodies or monoclonal antibodies increased the binding ability of porcine BPI to endotoxin. 同時(shí)抗人BPI多克隆抗體和單克隆抗體可增加豬源BPI的結合內毒素活性。
- Study of Purification of Recombinant Human Erythropoietin Produced with FBSFree Medium. 無(wú)血清培養基生產(chǎn)重組人紅細胞生成素的純化。
- Goat anti human IgG Fab antibody affinity chromatography column was prepared and the Fab supernant was purified. 制備羊抗人IgGFab抗體親和層析柱、純化Fab片段。
- BACKGROUND: Recombinant human erythropoietin is commonly used for treatment of anaemia. 背景:重組體人紅細胞生成素通常用于治療貧血。
- Amifostine(AMF)was used alone(4/12)or combined with recombinant human erythropoietin(rh-EPO)(8/12)in 12 MDS patients. 采用單用AMF或聯(lián)合紅細胞生成素(rhEPO)治療12例MDS患者,其中8位高齡患者采用AMF聯(lián)合rhEPO治療,4例單用AMF治療。
- Objective:To obtain human mouse chimeric Fab fragment of the anti human small cell lung cancer mAb 2F7 by means of engineering antibody. 目的 :通過(guò)基因工程抗體改造獲得具有與人小細胞肺癌有特異性反應的人 鼠嵌合抗體 2F7Fab片段。
- METHODS: The C5aR expressions on ERM tissue and cultured RPE cells were detected by ABC immunohistochemical staining with mouse anti human C5aR mcAbs. 另取新鮮人眼球 ,常規分離、培養人RPE細胞。 以小鼠抗人C5aR單克隆抗體作為檢測抗體 ,對PVR患者的ERM組織及培養的人RPE細胞做細胞免疫化學(xué)ABC染色 ,檢測C5aR的表達。
- Objective To prepare monoclonal antibody (McAb) against reconbinant human erythropoietin (rhEPO) and identify the biological features of the McAb. 目的研制特異性識別人促紅細胞生成素的單克隆抗體,并對其生物學(xué)特性作出初步鑒定。
- Methods Broth culture was used to observe the changes of bactericidal rate of porcine BPI with or without anti human BPI antibody. 方法 采用肉湯培養法測定BPI在有或無(wú)抗人BPI抗體存在情況下豬源BPI對大腸桿菌J5的殺菌率變化 ;
- OBJECTIVE This article introduces a method to study the bacterial endotoxin test for detecting pyrogen in recombinant human erythropoietin injection. 目的本文介紹了一種重組人紅細胞生成素注射液的細菌內毒素檢查法。
- RESULTS Recombinant human erythropoietin injection in 150-fold dilution had no inerference to the bacterial endotoxin test. 結果重組人紅細胞生成素注射液稀釋150倍對細菌內毒素檢查法無(wú)干擾。
- Anti human BPI polycolonal antibodies or monoclonal antibodies not only increase the bactericidal activity, but also increase the binding activity of porcine BPI to endotoxin. 抗人BPI多抗或單抗不僅能增加豬源BPI的殺菌活性 ,而且能增加其結合內毒素活性
- Unlike many biotechnology companies, 3SBio is profitable, largely because of its key product, EPIAO, an injectable recombinant human erythropoietin. 同許多生物技術(shù)公司不同的是,三生制藥是盈利的,這主要是因為該公司的核心產(chǎn)品益比奧(重組人紅細胞生成素)。
- Methods Anti human bladder carcinoma cell line BIU 87 monoclonal antibody BDI 1 was labelled with technetium 99m by direct mercaptoethanol reducing method. 方法采用抗人膀胱癌單克隆抗體BDI-1通過(guò)2-巰基乙醇直接還原法標記99mTc(99mTc)制備了99mTc-BDI-1。
- Mcnabon LP,Dawborn JK.Experience with low dose intranvenous and subcutaneous administration of recombinant human erythropoietin[J].Am J Nephol,1990,10(3):404. 吳俊;袁志忠;葉朝陽(yáng);等.;大劑量重組人紅細胞生成素治療尿毒癥貧血的療效觀(guān)察[J]
- Results 98% purity was reached through 14F7 monoclonal antibody column, and 95% purity was gained after goat anti human Fab fragment column. But yield ratio of the two affinity columns was low, being 35% and 55%, respectively. 結果3種純化方法中,14F7單克隆抗體柱純化的Fab抗體的純度達98%25左右,Fab抗體柱純化的Fab抗體的純度為95%25,但這兩種親和柱的目的蛋白收率都不高,分別為35%25、55%25。
- The results of detection of specific IgG4 in sera of 173 cerebral cysticercosis patients by dip test using gold labeled anti human IgG4 monoclonal antibody(McAb) were reported and compared with the case CT and MR scans. 應用金標抗人IgG4 McAb 浸測試驗檢測173 例腦囊蟲(chóng)病患者血清中特異IgG4,并與其腦CT、MR影像分型進(jìn)行對比分析。
- The company was able to produce a synthetic version of human erythropoietin (which boosts red blood cell production and commands a $5-billion market) that is more than twice as potent as the hormone brewed in hamster cells. 該公司能夠制造人造樣式的人類(lèi)紅血球生成素(可刺激紅血球的生成,擁有50億美元的市場(chǎng)),其效果要比從倉鼠細胞所產(chǎn)生的激素高出兩倍以上。
- After anti human BPI polycolonal antibodies or monoclonal antibodies having no bactericidal activities were added, bactericidal rate of porcine BPI increased. But the antibody not against BPI had no such improving bactericidal activity. 抗人BPI多克隆抗體和單克隆抗體加入后 ,豬源BPI的殺菌活性不僅不降低 ,反而增加 ,而抗體本身并不具有殺菌性 ,非抗BPI抗體也無(wú)此效應 ;