A dendritic affinity ligand (Artifical Protein A)was exsitu-synthesized for combining two biomimetic ligand N-cbz-L-Tyr and N-cbz-L-Asp with Gly-L-Gln as the agency. IgG was purified from human plasma using this new affinity adsorbent.
英
美
- 通過(guò)一個(gè)枝狀分子甘氨酸-L-谷氨酰胺(Gly-L-Gln),將IgG的兩個(gè)模擬配基N-cbz-L-Tyr和N-芐氧羰基-L-天冬氨酸(N-cbz-L-Asp)偶聯(lián)合成了一個(gè)枝狀親和配基,在實(shí)驗技能上實(shí)現了簡(jiǎn)單枝狀分子的異位合成(蛋白A仿生分子)。
