4 Chloro 4,5 dimethyl 1,3 dioxolan 2 one was synthesized from 3 hydroxy 2 butanone by acylation and cyclization, the yield was above 86%.

 
  • 以羥基丁酮為原料,經(jīng)?;?、環(huán)合等步驟合成醫藥中間體4氯4,5二甲基1,3二氧雜環(huán)戊烷2酮,合成收率達86%25以上
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