藥石罔效

- can't be cured by medicine; All medical treatment has failed.; All medicines have failed to effect a cure.; All medicines were tried and found useless.; be past treatment; Even medicine fails to make one feel better.; Medicines produce no effect.; No medicines [drugs] were of any avail.; One's illness seemed beyond the art of the leech and drugs seemed of no avail.; One was treated by the doctors with every available medicine, but without success.; The remedy proved to be quite ineffectual.