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- 由于A(yíng)IRE基因的突變可導致自身免疫病APECED(autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy,APECED),又稱(chēng)自身免疫性多腺體綜合征I(autoimmune polyg-landular syndrome type I, APS I)。Mutations in the AIRE gene were responsible for autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy (APECED), and also called autoimmune polyglandular syndrome type I(APS I), so the gene could play important roles in maintaining the self-tolerance and preventing the autoimmune disease.
